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Medusas are humanoids with serpents for hair, and scaly, reptilian skin. They are known to be able to petrify creatures with a glance, and frequently beguile their enemies into doing looking at them so that they can do turn them to stone.
Medusas appear as humans for the most part, but their hair is a nest of writhing snakes.
Medusas first appeared as "medusae" in the White Box set for OD&D.